Ingenious Fox

Ingenious strategies of microbial pathogens

Silencing innate immunity During infection, microbes traverse or invade a variety of biological niches in which they are challenged by the innate immune responses of host cells. Katherine Owen (Casanova lab, University of Virginia, Charlottesville) showed that intracellular Salmonella escape autophagosomal degradation by activating mTOR through the FAK/ Akt kinase pathway. This process requires...

An Ingenious Data Hiding Scheme for Color Retinal Image

Steganography is the art of communicating messages in a way such that only the intended recipient knows of their existence. In this paper, we present a novel steganographic method, that can transmit the embedded secret data effectively and securely. The proposed data hiding method makes use of color retinal images as the cover media and employs the least significant bit method to embed secret b...

An Ingenious Filter: the Structural Basis for Ion Channel Selectivity

channel from Streptomyces lividans, was readily overex-pressed in bacteria (Schrempf et al., 1995). Its primary sequence is related to the class of ion-selective channels called inwardly rectifying channels, as evidenced by the presence of two putative transmembrane helices with the ion selectivity–determining P region residing Neurobiology has taken a giant step forward: we know, between them ...

When a common problem meets an ingenious mind.

When the marvels of modern biological research are presented in the media, one image almost always appears: a person in a laboratory using a micropipette. This small but ubiquitous device has evolved into one of the icons of modern biotechnology, molecular biology, gene therapy, stem-cell technology and cloning. The modern micropipette has achieved such high visibility for obvious reasons: it i...

The Long Fox Lecture